The recommended starting dose is 30 mg (given as a single 30 mg tablet or as 1/2 of a 60 mg tablet) or 60 mg (given as a single tablet) once daily. After several days, the dosage may be increased to 120 mg (given as a single 120 mg tablet or as two 60 mg tablets) once daily. Rarely, 240 mg may be required. It should be taken in the morning on arising, or as prescribed by the physician.
Isosorbide Mononitrate sustained release should not be chewed or crushed and should be swallowed together with a half-glassful of fluid.